(1S,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide hydrochloride - Names and Identifiers
Name | (1S,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide hydrochloride
|
Synonyms | Saxaint-E Saxagliptin Intermediate 5 l-cis-4,5-MethanoprolinaMide hydrochloride (1R,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide (1S,3S,5S)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXAMIDE HCL (1S,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxaMide hydrochloride (1S,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide hydrochloride (1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide hydrochloride
|
CAS | 709031-39-0
|
EINECS | 1308068-626-2 |
(1S,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide hydrochloride - Physico-chemical Properties
Molecular Formula | C6H11ClN2O
|
Molar Mass | 162.62 |
Density | 1.238g/cm3 |
Melting Point | >192°C (dec.) |
Boling Point | 331.93°C at 760 mmHg |
Flash Point | 154.546°C |
Solubility | DMSO (Slightly), Water (Slightly) |
Vapor Presure | 0mmHg at 25°C |
Appearance | Solid |
Color | Pale Orange |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.552 |
(1S,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide hydrochloride - Introduction
Nature:
-Appearance: White crystalline solid
-Molecular formula: C6H11ClN2O
-Molecular weight: 164.62g/mol
-Melting point: 144-146°C
-Solubility: Soluble in water and some organic solvents
Use:
-It is an important organic synthesis intermediate and has a wide range of applications in drug synthesis.
-can be used for the preparation of antibacterial drugs, antiepileptic drugs and analgesic drugs.
Preparation Method:
(1S,3S,5R)-2-Azabicyclo[3.1.0] There are many ways to prepare hexane-3-carboxamide hydrochloride. The following is a common synthesis method:
1. take azabicyclohexane (azabicyclohexane) and carbonyl chloride reaction, get the corresponding N-formylation products.
2. The N-formylation product reacts with hydrogen chloride to generate hydrochloride.
Safety Information:
-In case of contact, please use appropriate personal protective measures, such as wearing gloves, goggles and laboratory coats.
-Avoid inhalation, ingestion or skin contact to avoid discomfort or damage.
-When using or storing, please follow the safety procedures and ensure proper exhaust and ventilation.
-If necessary, consult the relevant safety data form for more information.
Please note that the specific properties and uses of this compound may require further understanding and evaluation in a specific research context. Always follow proper laboratory and safe operating procedures when using or handling any chemical.
Last Update:2024-04-09 19:05:51